We examine the impact of publicly funded biomedical research on the in-house research of the for-profit pharmaceutical industry. Qualitative analysis of the history of the discovery and development of a sample of 21 significant drugs, and a program of interviews with senior managers and...

Coe and Helpman(1995) have measured the extent to which technology spills over between industrialized countries through the particular channel of trade flows. This paper re-examines two particular features of their study. First, we suggest that their functional form of how foreign R&D affects...

This paper examines available U.S. data on academic R&D expenditures and the number of papers published and the number of citations to these papers as possible measures of `output' of this enterprise. We look at these numbers for science and engineering as a whole, for 5 selected major fields,...

Individuals involved in basic research, like other workers, respond to incentives. Funding agencies provide implicit incentives when they specify the rules by which awards are made. The following analysis is an exercise in understanding incentives at an applied level. Specific rules are examined...

This paper applies a rational action/economic sociology approach to the central organizational theory question of whether action is embedded in pre-formed institutions that are relatively cheap in terms of time and energy, or to what extent action becomes embedded in newly constructed...

Investment in research and development (R&D) affects a country's total factor productivity. Recently new theories of economic growth have emphasized this link and have also identified a number of channels through which a country's R&D affects total factor productivity of its trade partners....

We explore the use of patent citations to measure the "basicness" and appropriability of inventions. We propose that the basicness of research underlying an invention can be characterized by the nature of the previous patents cited by an invention; that the basicness of research outcomes relates...

About 20 percent of the gross investment expenditures of U.S. manufacturing firms is expenditures on research and development. Like investment in physical capital, R&D also responds to news about future prospects of the firm, such as profitability, technological opportunities, or changes in...

Forecasts of experimental results can clarify the interpretation of research results, mitigate publication bias, and improve experimental designs. We collect forecasts of the results of three Registered Reports preliminarily accepted to the Journal of Development Economics, randomly varying four...

New ideas no longer fuel economic growth the way they once did. A popular explanation for stagnation is that good ideas are harder to find, rendering slowdown inevitable. We present a simple model of the lifecycle of scientific ideas that points to changes in scientist incentives as the cause of...